Certified Nephrology Nurse Certification (CNN) Practice Exam 2025 - Free Nephrology Nursing Practice Questions and Study Guide

The diagnosis of Pyelonephritis primarily relies on specific laboratory tests that help identify the presence of infection and inflammation in the kidneys. Commonly, blood culture is utilized to identify any bacteria present in the bloodstream, while urinalysis helps detect the presence of white blood cells, bacteria, and protein in the urine, which are indicative of a urinary tract infection. Additionally, urine culture is performed to isolate the causative organism, confirming the presence of bacteria and guiding appropriate antibiotic therapy.

This combination of tests is critical for establishing the diagnosis of Pyelonephritis, as it directly assesses kidney function and the presence of infection, rather than relying on imaging or less relevant diagnostic methods. Other options such as an electrocardiogram focus on cardiac assessment, while Magnetic Resonance Imaging and biopsy are not standard for diagnosing this condition. Similarly, chest X-rays and blood pressure monitoring do not provide pertinent information regarding renal infections. Thus, the combination of blood culture, urinalysis, and urine culture is the correct and standard approach for diagnosing Pyelonephritis.