Certified Nephrology Nurse Certification (CNN) Practice Exam 2026 - Free Nephrology Nursing Practice Questions and Study Guide

Penicillin G is primarily eliminated from the body through renal excretion, and a significant portion of it is excreted unchanged in the urine. Typically, about 80% of the administered dose of Penicillin G is recovered in the urine as unchanged drug. This high percentage demonstrates the efficiency of the kidneys in filtering and excreting this antibiotic, which is critical for its therapeutic effectiveness. Understanding this percentage is important for nephrology nurses as it highlights the potential need for dose adjustments in patients with renal impairment, ensuring effective and safe use of Penicillin G in clinical settings.